Does Anyone Know If It Is Possible To Offer Advertisers One’s Own Affiliate Scheme I.e. Cut Out The Middle Man?

As long as it isn’t VERY difficult technically (or I could pay someone to do it myself if it’s not horribly expensive).
I am making a website which should be VERY successful as it is ‘one of a kind’ & should corner the market in one particular area of UK tourism. This being the case, I’d like to offer my own affiliate scheme for hotels, B & Bs, Self Catering accommodation, Car Hire, Transport etc. so if a booking is made I get a percentage of a sale that came through my website.
Is this pie in the sky or relatively plausible? I’m a bit concerned that advertisers themselves will be put off by complicated procedures -or are they fairly easy to implement? e.g. Add a single line of code to their website perhaps?
Having said all that does this sound unrealistic & would I be better off using an affiliate company or Google?

Incoming search terms:

• tourism affiliate program uk (1)